PE Anti-Mouse CD326/EpCAM Antibody [G8.8]

Monoclonal PE-conjugated antibody for mouse EpCAM/CD326 detection by flow cytometry.

Product Description

PE Anti-Mouse CD326/EpCAM Antibody [G8.8] is a rat monoclonal antibody designed to detect mouse epithelial cell adhesion molecule (EpCAM), also known as CD326. Conjugated to phycoerythrin (PE), this antibody is suitable for fluorescent detection of EpCAM-expressing cells by flow cytometry.

EpCAM is a transmembrane glycoprotein involved in calcium-independent homophilic cell-to-cell adhesion. It is associated with epithelial cell organization, proliferation and tumor biology, making it an important marker in immunology, cancer research and stem cell studies.

Background

EpCAM mediates calcium-independent homophilic cell-to-cell adhesion and may also function as a growth factor receptor. It is thought to contribute to maintaining cell positioning during proliferation. Its expression can correlate inversely with E-cadherin (CD324) levels. EpCAM is widely investigated in epithelial cell biology and tumor research.

Key Features

• Rat monoclonal antibody, clone G8.8
• Specific reactivity with mouse EpCAM/CD326
• PE fluorescent conjugation
• Designed for flow cytometry (FCM)
• Suitable for epithelial cell and tumor biology research
• Recommended concentration: 5 μL per test

Applications

• Flow cytometry analysis of EpCAM-expressing cells
• Epithelial cell identification and characterization
• Immunology research
• Stem cell research
• Cancer and tumor biology studies
• Cell population phenotyping

Technical Specifications

Recommended Usage

Use 5 μL of antibody per test, corresponding to approximately one million cells in a 100 μL staining volume or per 100 μL of whole blood. Optimize staining conditions according to the experimental sample and protocol.

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