GHRH Peptide Growth Hormone Releasing Hormone
GHRH Peptide (Growth Hormone Releasing Hormone)
Product Overview
Growth Hormone Releasing Hormone (GHRH) is a synthetic peptide corresponding to the human hypothalamic hormone responsible for stimulating growth hormone secretion from the anterior pituitary gland. This peptide is widely used in endocrinology, neurobiology, and peptide research applications.
Research Use Only. Not intended for diagnostic or therapeutic applications.
Product Information
| Parameter | Description |
|---|---|
| Product Name | Growth Hormone Releasing Hormone (GHRH) Peptide |
| Full Name | Growth Hormone Releasing Factor (1-40) amide (human) |
| Gene Symbol | GHRH |
| Synonyms | GHRF, GRF, Somatoliberin, Somatocrinin |
| Host | Synthetic Peptide |
| Species Reactivity | Human |
| Molecular Weight | 12,447 Da |
| Purity | ≥95% (HPLC Purified) |
| Appearance | Lyophilized Powder |
| Applications | Research, Endocrinology Studies, Hormone Research |
| Storage Temperature | -20°C |
Sequence
Linear Sequence:
Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-NH₂
Gene Information
- Gene Symbol: GHRH
- Chromosomal Location: 20q11.2
- Gene ID: 2691
- Protein Family: Glucagon Family
- Protein Name: Somatoliberin
Biological Function
GHRH is synthesized in the hypothalamus and acts on the anterior pituitary gland to stimulate the secretion of growth hormone. The peptide plays an essential role in regulating growth, metabolism, and endocrine function.
Research has demonstrated that GHRH receptors are expressed in various tissues and certain tumor types, making this peptide valuable in endocrine and oncology research.
Applications
- Growth hormone regulation studies
- Endocrine system research
- Neuroendocrine investigations
- Receptor binding studies
- Peptide biology research
- Cell signaling studies
- Hormonal pathway analysis
Purification
The peptide is highly purified using high-performance liquid chromatography (HPLC), ensuring excellent purity and consistency suitable for laboratory applications.
Storage and Stability
- Store lyophilized material at 4°C for short-term use.
- For long-term storage, keep at -20°C.
- Avoid repeated freeze-thaw cycles.
- Reconstituted solutions should be aliquoted and stored frozen.
The product remains stable for up to 12 months under recommended storage conditions.
Handling Instructions
Prior to opening, briefly centrifuge the vial to collect all material at the bottom. Reconstitute using sterile water or an appropriate buffer according to your experimental requirements.
Further dilutions may be prepared using suitable assay buffers.
Research Areas
- Endocrinology
- Peptide Research
- Hormone Biology
- Neuroscience
- Cell Signaling
- Molecular Biology
References
Recent studies have investigated the role of GHRH in:
- Growth hormone regulation.
- Neuroendocrine signaling pathways.
- Tumor receptor expression.
- Metabolic regulation.
- Brain function and neurotransmitter modulation.
Disclaimer
This product is intended exclusively for scientific research purposes. It is not intended for human or veterinary use, therapeutic applications, or diagnostic procedures.
Users are responsible for determining the suitability of this product for their specific research applications and for handling the material according to established laboratory safety guidelines.