AlbuVoid™ Kit - 10 preparations

AlbuVoid™ Kit – 10 Preparations (AVK-10)

The AlbuVoid™ Kit (10 preparations) is a specialized albumin depletion and low-abundance protein enrichment kit designed for serum and plasma sample preparation in proteomics workflows.

SHOP NOW

Product Overview

  • Type: Albumin depletion reagent kit
  • Capacity: 10 preparations (≈ 10 × 200 µL samples)
  • Application: Proteomics, biomarker discovery, LC-MS, MALDI-TOF, gel electrophoresis
  • Format: Spin-filter based workflow

Principle of the Kit

Unlike traditional affinity methods:

  • AlbuVoid™ does NOT bind albumin
  • Instead, it binds all other proteins, allowing:
    • Albumin → remains in flow-through
    • Target proteins → retained and eluted

Result: Efficient enrichment of low-abundance proteins

 Key Features

  • >95% albumin removal (voided in flow-through)
  • Enhances detection of proteins < 50 kDa
  • Rapid protocol (~30 minutes)
  • Maintains native protein structure and enzymatic activity
  • No columns → no regeneration or cross-contamination
  • Works across multiple species (human, mouse, bovine, etc.)

    Kit Components (10 Preps)

    • AlbuVoid™ binding matrix (~0.5 g)
    • Binding buffer (pH ~6.0)
    • Wash buffer (pH ~7.0)
    • Elution buffer (pH ~9.8–10)
    • Spin filter tubes (×10)

    Applications

    Ideal for:

    • Biomarker discovery (liquid biopsy, cancer research)
    • LC-MS / proteomics workflows
    • 1D / 2D gel electrophoresis
    • Protein arrays & cytokine profiling
    • Enzyme activity studies

    Why Use AlbuVoid™ Instead of Classical Methods?

    Feature AlbuVoid™ Immunoaffinity / Dye-based
    Albumin removal strategy Negative selection Positive binding
    Protein recovery High (low-abundance enriched) Often biased
    Cost & reuse Disposable, low cost Expensive columns
    Protein integrity Preserved Sometimes altered

    Scientific Insight

    Albumin represents ~60% of total serum protein, masking low-abundance biomarkers.
    AlbuVoid™ solves this by:

    • Removing dominant proteins
    • Increasing analytical sensitivity

    Improving downstream detection in mass spectrometry and proteomics